1. Usulelo lokuphefumla kunye ne-coinfection eneempawu ezifanayo
Kwiminyaka yakutshanje, izifo ezosulelayo zokuphefumla ziyindawo edumileyo yophando lwempilo yoluntu.Abantwana, abantu abadala, abangondlekanga, kunye nezigulana ezinganyangekiyo ngamaqela asesichengeni.Kodwa izifo ezosulelayo zomgudu wokuphefumla zisisongelo sempilo esiqhelekileyo phantse kubo bonke abantu.
Izifo zokuphefumula zizifo ezibangelwa yi-microorganisms ezihlasela kwaye zikhule kwindlela yokuphefumula.Olu sulelo lubandakanya izifo zendlela yokuphefumula ephezulu kunye nezifo ezisezantsi zokuphefumula, usebenzisa i-larynx njengomda.
Iintsholongwane eziphambili ezibangela usulelo lokuphefumla ziintsholongwane, ibhaktheriya, umngundo kunye neentsholongwane ezingaqhelekanga.Iintsholongwane ikakhulu ziquka intsholongwane yomkhuhlane, intsholongwane yeparainfluenza, intsholongwane yokuphefumla i-syncytial virus (RSV), kunye ne-adenovirus (ADV).Iibhaktheriya eziqhelekileyo ziquka i-Haemophilus influenza, pneumococcus, kunye ne-staphylococcus.Iifungi eziqhelekileyo ziquka iCandida albicans kunye nePneumocystis jiroveci.Iintsholongwane ze-Atypical ziquka i-mycoplasma, i-chlamydia, njl.
Iimpawu zeklinikhi zokusuleleka kwintsholongwane yokuphefumula ziyinkimbinkimbi kunye nokubonakaliswa kweklinikhi efanayo.I-pathogen efanayo inokubangela iimpawu ezininzi zeklinikhi, kwaye iimpawu ezifanayo zeklinikhi zinokubangelwa zizifo ezininzi.Ke, akunakwenzeka ukuxilonga ngokuchanekileyo i-pathogen eyosulela ngeempawu zeklinikhi.Kwangaxeshanye, kukwakho ne-coinfections ebangela imingeni eyongezelelekileyo yokuxilongwa kweklinikhi.
2. Iteknoloji yokufumanisa i-PCR
Kukho iindlela ezahlukeneyo zokuxilongwa kweentsholongwane zokuphefumula, ezichazwe ngezantsi.
Phakathi kokufunyaniswa kwesintu, iX-reyi yesifuba kunye novavanyo lwegazi lwesiqhelo lunovakalelo oluphantsi kunye neenkcukacha ezithile zosulelo lwentsholongwane ephilayo yentsholongwane.
Inkcubeko ezimeleyo igxininise ngakumbi kodwa kunye nezinga eliphantsi lokufumanisa okulungileyo, ixesha elide lokubona, ubunzima bokuqokelela iisampuli ukusuka kwindlela yokuphefumula ephantsi, amathuba aphezulu okungcola, kunye nobunzima bokufumanisa amanqanaba aphantsi entsholongwane.
Ukufunyaniswa kwe-antibody ethe ngqo kwi-Immunology kuphenjelelwa yi-antibody kinetics, kwaye iipathogens zinokubangela kuphela iimpawu zokuphefumla emva kokuba zihlasele iiseli ekujoliswe kuzo kwaye zande ngokusebenzayo.Ke, i-pathogen inokuchongwa ngokuchongwa kwe-antigen, kodwa uvakalelo lobu buchule bokubona buphantsi.
Ngokuqhubekayo ngokutsha, ukukhuthazwa, kunye nokusetyenziswa kweteknoloji yebhayoloji ye-molekyuli, ukufunyanwa kwe-PCR kuye kwanda.Xa kuthelekiswa nobuchule bokubona bemveli, itekhnoloji yokuvavanya i-PCR kulula ukubona iintsholongwane zezifo zokuphefumla.Ngexesha elifanayo, ichanekile kakhulu, igcina ixesha, kwaye inokuchonga i-pathogenic microorganisms ye-coinfections.
3. Indibaniselwano yasimahla yee-reagents ze-PCR ze-Hecin
Ukufumanisa ngokukhawuleza ukusuleleka kwintsholongwane yokuphefumula kubalulekile ukucacisa i-pathogens ukukhuthaza unyango olujoliswe kuyo kunye nokunciphisa umonakalo kwizigulane.
I-Hecin ithatha umsebenzi wokukhusela impilo yabantu yokuphefumla, ihlala igxininisa kwingcamango yophando oluzimeleyo kunye nokutsha.I-Hecin ihlakulela ngokunzulu ekuphuhlisweni kwee-reagents zokuxilonga kwizifo ezosulelayo eziphefumulayo.
Ii-reagents zovavanyo ze-PCR ze-Hecin zenziwe ngeetyhubhu ezilodwa, ezinokudityaniswa ngokuguquguqukayo ngaphandle komda.Ezi reagents kunokubangela ukufunyanwa ngaxeshanye pathogens ezininzi kwisampulu enye, ukusombulula ingxaki ukubonakaliswa efanayo kwezonyango kwaye kaninzi coinfections kuxilongo lwezonyango.
Okwangoku, i-Hecin ine-CE-certified PCR reagents enokuthi idityaniswe ngokukhululekileyo ukuze ibone iindidi ezili-11 zentsholongwane yokuphefumla:
1)I-COVID 19
2)IAV
3)IBV
4)ADV
5)RSV
6)PIV1
7)PIV3
8)MP
9)HBoV
10)EV
11)EV71
Ii-reagents ze-PCR ze-Hecin zovavanyo oluphezulu kunye nokusebenza okulula, zifanelekile ukuxilongwa ngokukhawuleza kwezifo ezibangelwa yi-pathogens yokuphefumula, kwaye zihambelana neqonga le-PCR le-fluorescent.
Ii-reagents ze-PCR ze-Hecin zenziwa kwi-reagent ye-powder eyomileyo, enozinzo olomeleleyo kwaye inokuhanjiswa kwaye igcinwe kwiqondo lokushisa, ukuphelisa inkathazo yokuhamba kunye nokugcinwa kwekhonkco elibandayo.Izinto zovavanyo ezahlukeneyo zenziwe ngemibala eyahlukeneyo, okwenza kube lula ukwahlula.Umsebenzi ulula kwaye ulungele, kwaye umqhubi akayidingi imisebenzi enzima yokupakisha ngesandla.
Ngexesha le-post-COVID, ukuchongwa kweentsholongwane zokuphefumla kunikwa ingqalelo engakumbi nangakumbi.Kubaluleke kakhulu ukubonelela ngeziphumo zovavanyo oluthembekileyo lwe-pathogenic ngokukhawuleza.UHecin uzibophelele ekuboneleleni ngokuchaneka ngakumbi, uvakalelo, uncedo, kunye neemveliso zoxilongo olukhawulezayo kubathengi bethu.
Ixesha lokuposa: Feb-17-2023